Numerous randomized controlled trials have examined a wide range of pharmacological agents for the treatment of HF with reduced ejection fraction (HFrEF), usually defined as an ejection fraction <45%. A detailed review of agents shown to be effective in reducing mortality or symptoms in HFrEF is beyond the scope of this document, but issues relevant to their use in SNFs will be briefly discussed.

Diuretic Representatives

Diuretic agents was an extremely important component regarding HF danger sign management and remain the greatest agencies for repairing pulmonary congestion and you will edema. 46 However, even though diuretic representatives get rid of attacks and you can boost total well being, there’s no evidence which they disappear mortality. Diuretic representatives and additionally trigger neurohormones, and you may findings regarding tendency-paired training during the more mature HF patients suggest that persistent diuretic medication could possibly get boost risk to have dying and you will hospitalization. 51 Diuretic dosage can be modified to maintain euvolemia, and thus reducing symptoms and you may increasing well being while you are reducing the latest negative effects from diuretic cures. Diuretic agents wanted mindful monitoring of frequency standing (playing with lbs and real examination), renal function, electrolytes, and you can orthostatic blood demands. Once euvolemia try achieved, people shall be addressed with a minimal serving to keep up that reputation. Leer más